Preimplantation Genetic Diagnosis: Chances of Successful Pregnancy and Birth

With the help of preimplantation genetic diagnosis (PGD), scientists can examine with a greater degree of accuracy, the appearance of an embryo or oocyte to determine whether it is healthy. They can examine whether such oocytes also have normal genetic codes that have no genetic faults. By using PGD, the chances of a successful single IVF cycle have increased tremendously. This has doubled the chances of a healthy pregnancy and decreased the chances of multiple pregnancies. The implantation rates have also increased significantly since embryos that are genetically normal are implanted using PGD.

Advantages of PGD

PGD helps ensure that only embryos that provide a chance of healthy pregnancy are implanted in the uterus for development into a child. Research has shown that PGD is more than 98 percent accurate in identifying genetic abnormalities in oocytes. This allows the physician to discard use of abnormal oocytes and to use only proper oocytes for implantation, thereby decreasing the risk of IVF failure and miscarriage.

Thus, the use of PGD technology prevents miscarriages and the birth of children with genetic abnormalities. It can be used successfully for parents with a medical condition. The risk of carrying multiple children is also eliminated by this technology. PGD technology can be used in couples with a history of failed IVF or on mothers who suffer from premature menopause.

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