What Special Precautions Should I Follow When Taking Prednisone?

Prednisone is among the more commonly recommended medications for treating infertility among women. However, this medication should be used in accordance with some basic precautions.

Prednisone Precautions

Before starting a Prednisone regimen, inform you healthcare provider if you have any of the following conditions:

  • High blood pressure/hypertension
  • Fungal infections
  • Hypothyroidism
  • Diabetes
  • Osteoporosis
  • Liver diseases
  • Infection or allergy (history of allergic reactions to medications)
  • Ulcers
  • Myasthenia gravis
  • Kidney diseases (particularly, renal failure)
  • Stressful lifestyle, particularly if you are taking anti-depressants or anxiolytics drugs

Share information about prescription and non-prescription medicines or supplements that you are currently using or you have used in the recent past. Prednisone is known to weaken the immune system to some extent. If you have medical history of repeatedly falling ill or are particularly vulnerable to a certain kind of infection/disease, inform the healthcare practitioner about the pattern in which that particular condition surfaces.


Prednisone can cause some typical problems during the initial few weeks. This includes increased strain on the eyes. This should be reported to your physician since unresolved strain or discomfort is often an indication of a developing cataract or conditions like glaucoma.

Mood Changes

Prednisone can induce some mood-related changes. Some degree of insomnia or agitation is expected but if your behavioural pattern seems to have changed drastically after starting Prednisone, you might need a lower dosage. Failure to correct the dosage can cause hallucinations and bouts of uncontrolled aggression.

Other Medications & Stopping Prednisone

Never stop or alter the regimen of Prednisone without prior discussion with your healthcare provider. Prednisone is known to induce some disturbing withdrawal symptoms if stopped suddenly. Some common medications like aspirin and regular vaccinations can contra-react with Prednisone. Always seek medical consultation before using any medication/drug during a Prednisone regimen, even over-the-counter medications.

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